Please feel free forward to your colleagues and share the news of our journal | Indexed in: PubMed/MEDLINE Web of Science Scopus | Volume 79, Issue 4 / 2021 Online EDITOR'S CHOICE REVIEW ARTICLE Deciphering Alzheimer’s Disease Pathogenic Pathway: Role of Chronic Brain Hypoperfusion on p-Tau and mTOR de la Torre, Jack C. REVIEW ARTICLES Neurodevelopmental and Neurodegenerative Similarities and Interactions: A Point of View About Lifelong Neurocognitive Trajectories Magnin, Eloi Relationship Between Chronic Noise Exposure, Cognitive Impairment, and Degenerative Dementia: Update on the Experimental and Epidemiological Evidence and Prospects for Further Research Huang, Lei | Zhang, Yang | Wang, Yongwei | Lan, Yajia Therapeutic Strategies Targeting Amyloid-β Receptors and Transporters in Alzheimer’s Disease Lao, Kejing | Zhang, Ruisan | Luan, Jing | Zhang, Yuelin | Gou, Xingchun Sleep Deprivation, a Link Between Post-Traumatic Stress Disorder and Alzheimer’s Disease Delic, Vedad | Ratliff, Whitney A. | Citron, Bruce A. EDITOR'S CHOICE RESEARCH ARTICLES Visual Memory Deficits in Middle-Aged APOE ɛ4 Homozygotes Detected Using Unsupervised Cognitive Assessments Lim, Yen Ying | Pase, Matthew P. | Buckley, Rachel F. | Yassi, Nawaf | Bransby, Lisa | Fowler, Christopher | Laws, Simon M. | Masters, Colin L. | Maruff, Paul Disorientation in Time and Place in Old Age: Longitudinal Evidence from Three Old Age Cohorts in Germany (AgeDifferent.de Platform) Rodriguez, Francisca S. | Pabst, Alexander | Heser, Kathrin | Kleineidam, Luca | Hajek, Andre | Eisele, Marion | Röhr, Susanne | Löbner, Margrit | Wiese, Birgitt | Angermeyer, Matthias C. | et al. Association of Malnutrition with Functional and Cognitive Trajectories in People Living with Dementia: A Five-Year Follow-Up Study Borda, Miguel Germán | Ayala Copete, Ana María | Tovar-Rios, Diego Alejandro | Jaramillo-Jimenez, Alberto | Giil, Lasse Melvær | Soennesyn, Hogne | Gómez-Arteaga, Camilo | et al. Putative Blood Somatic Mutations in Post-Traumatic Stress Disorder-Symptomatic Soldiers: High Impact of Cytoskeletal and Inflammatory Proteins Sragovich, Shlomo | Gershovits, Michael | Lam, Jacqueline C.K. | Li, Victor O.K. | Gozes, Illana RESEARCH ARTICLES Interleukin-6 Interacts with Sleep Apnea Severity when Predicting Incident Alzheimer’s Disease Dementia Baril, Andrée-Ann | Beiser, Alexa S. | Redline, Susan | McGrath, Emer R. | Gottlieb, Daniel J. | Aparicio, Hugo | Seshadri, Sudha | Himali, Jayandra J. | Pase, Matthew P. Declining Use of Potentially Inappropriate Medication in People with Dementia from 2000 to 2015: A Repeated Cross-Sectional Nationwide Register-Based Study – Open Access Kristensen, Rachel Underlien | Jensen-Dahm, Christina | Gasse, Christiane | Waldemar, Gunhild | Indexed in: PubMed/MEDLINE Web of Science Scopus | Volume 79, Issue 3 / 2021 Online REVIEW ARTICLES Broader Insights into Understanding Tumor Necrosis Factor and Neurodegenerative Disease Pathogenesis Infer New Therapeutic Approaches – Open Access Clark, I.A. | Vissel, B. The Role of Traffic-Related Air Pollution on Neurodegenerative Diseases in Older People: An Epidemiological Perspective Streit, Wolfgang J. | Khoshbouei, Habibeh | Bechmann, Ingo The Role of Microglia in Sporadic Alzheimer’s Disease Streit, Wolfgang J. | Khoshbouei, Habibeh | Bechmann, Ingo Potential Impacts of Extreme Heat and Bushfires on Dementia Farugia, Taya L. | Cuni-Lopez, Carla | White, Anthony R. EDITOR'S CHOICE RESEARCH ARTICLES Effects of COVID-19 Home Confinement on Mental Health in Individuals with Increased Risk of Alzheimer’s Disease – Open Access (View Press Release) Soldevila-Domenech, Natalia | Forcano, Laura | Boronat, Anna | Lorenzo, Thais | Piera, Iris | Puig-Pijoan, Albert | Mateus, Julian | González de Echevarri Gómez, José María | et al. Metabolites Associated with Early Cognitive Changes Implicated in Alzheimer’s Disease Darst, Burcu F. | Huo, Zhiguang | Jonaitis, Erin M. | Koscik, Rebecca L. | Clark, Lindsay R. | Lu, Qiongshi | Kremen, William S. | Franz, Carol E. | Rana, Brinda | Lyons, Michael J. | et al. Hemochromatosis Mutations, Brain Iron Imaging, and Dementia in the UK Biobank Cohort – Open Access (View Press Release) Atkins, Janice L. | Pilling, Luke C. | Heales, Christine J. | Savage, Sharon | Kuo, Chia-Ling | Kuchel, George A. | Steffens, David C. | Melzer, David Could Altered Evoked Pain Responsiveness Be a Phenotypic Biomarker for Alzheimer’s Disease Risk? A Cross-Sectional Analysis of Cognitively Healthy Individuals – Open Access Romano, Raymond R. | Carter, Michael A. | Dietrich, Mary S. | Cowan, Ronald L. | Bruehl, Stephen P. | Monroe, Todd B. An Active Lifestyle Is Associated with Better Cognitive Function Over Time in APOE ɛ4 Non-Carriers Fernández-Matarrubia, Marta | Goni, Leticia | Rognoni, Teresa | Razquin, Cristina | Fernández-Lázaro, César Ignacio | Bes-Rastrollo, Maira | Martínez-González, Miguel Ángel | Toledo, Estefanía Could Altered Evoked Pain Responsiveness Be a Phenotypic Biomarker for Alzheimer’s Disease Risk? A Cross-Sectional Analysis of Cognitively Healthy Individuals – Open Access Romano, Raymond R. | Carter, Michael A. | Dietrich, Mary S. | Cowan, Ronald L. | Bruehl, Stephen P. | Monroe, Todd B. | In the News News releases that have been issued for content published in JAD has resulted in the research getting a lot of press coverage! Recent press releases include: February 2021 Spinal Fluid of People with Alzheimer’s Risk Gene Signals Inflammation Press Release | Study | Tweet | Facebook Post Research Establishes a New Method to Predict Individual Risk of Cognitive Decline Press Release | Study | Tweet | Facebook Post Air Pollution Poses Risk to Thinking Skills in Later Life, a Study Says Press Release | Study | Tweet | Facebook Post Psychological Distress of Lockdown in Pre-Dementia Patients Prolonged During the COVID-19 De-Escalation Press Release | Study | Tweet | Facebook Post Dementia Rates Higher in Men with Common Genetic Disorder Haemochromatosis Press Release | Study | Tweet | Facebook Post If you are on social media, we appreciate if you could spread the word about the above news items | Most Read Content in January 2021 Most read content via the IOS Press content website published in 2020 & 2021 JAD issues Neurobiology of COVID-19 – Openly Available (Review Article in Vol.76, Iss.1, 2020) Fotuhi, Majid | Mian, Ali | Meysami, Somayeh | Raji, Cyrus A. COVID-19: Review of a 21st Century Pandemic from Etiology to Neuro-psychiatric Implications – Open Access (Review Article in Vol.77, Iss.2, 2020) Yamamoto, Vicky | Bolanos, Joe F. | Fiallos, John | Strand, Susanne E. | Morris, Kevin | Shahrokhinia, Sanam | Cushing, Tim R. | Hopp, Lawrence | Tiwari, Ambooj | Hariri, Robert | Sokolov, Rick | et al. Alzheimer’s Disease and Face Masks in Times of COVID-19 – Openly Available (Review Article in Vol.79, Iss.1, 2021) Gil, Roger | Arroyo-Anlló, Eva M. Death Rate Due to COVID-19 in Alzheimer’s Disease and Frontotemporal Dementia – Openly Available (Research Article in Vol.78, Iss.2, 2020) Matias-Guiu, Jordi A. | Pytel, Vanesa | Matías-Guiu, Jorge Aluminum and Amyloid-β in Familial Alzheimer’s Disease – Open Access (Research Article in Vol.73, Iss.4, 2020) Mold, Matthew | Linhart, Caroline | Gómez-Ramírez, Johana | Villegas-Lanau, Andrés | Exley, Christopher Artificial Intelligence, Speech, and Language Processing Approaches to Monitoring Alzheimer’s Disease: A Systematic Review – Open Access (Research Article in Vol.78, Iss.4, 2020) de la Fuente Garcia, Sofia | Ritchie, Craig W. | Luz, Saturnino | Please share the JAD Newsletter with your colleagues! | If you know any colleagues and fellow researchers who are not signed up to receive the JAD newsletter, we invite you to share this mailing with them. They can sign up at: tiny.cc/JADsignup We hope news of our open access Journal of Alzheimer's Disease Reports will also be of interest? 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