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StemJournal | First Research Article Published

Dear Colleague,

Our journal's key priority is to publish top quality stem cell research and, on that point, we are very pleased to announce the publication of StemJournal's very first Research Article – more details available below.

We are inviting submissions for the journal, whether you wish to submit a new Review, Research Article, Protocol, Position Paper, or Poster Report. Discover full details on how to submit your research on our website.

Looking forward to working with you.

Kind regards,
Editors-in-Chief

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New Open Access Content!

Human Pluripotent Stem Cell-Derived Organoids as a Model of Intestinal Xenobiotic Metabolism

Sasaki, Kengo | Inoue, Makoto | Machida, Masakazu | Kawasaki, Tomoyuki | Tsuruta, Satoru | Uchida, Hajime | Sakamoto, Seisuke | Kasahara, Mureo | Umezawa, Akihiro | Akutsu, Hidenori

The human intestine is the site of absorption and first-pass metabolism for oral intake. Assessment of absorption, distribution, metabolism, excretion, and toxicity (ADMET) of xenobiotics has transformed the understanding of in vivo pharmacology. However, these processes are difficult to recapitulate in vitro. In this study, a simple protocol was developed for the generation of mature functional intestinal organoids from human pluripotent stem cells under xenogeneic-free conditions. The team sought to characterize transcription level in drug transporters and metabolism and evaluate CYP3A4 catalytic function of the organoids. Read Article

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Call for Papers

The journal publishes original, peer-reviewed Research Reports (plus Short Reports and Hypotheses), Seminal Reviews, Topical Reviews, Comparative Reviews, Ethics Reviews, and Protocols, covering a wide range of topics related to stem cell research.

Topics covered by StemJournal include the following:

▪ Cancer stem cells
▪ Cell maturation and aging
▪ Cellular and nuclear reprogramming
▪ Computational biology and data science
▪ Disease modeling and drug discovery
▪ Ectoderm specification and differentiation
▪ Endoderm specification and differentiation
▪ Genetics and epigenetics
▪ Genomics, proteomics and omics
▪ Germ cell and somatic stem cell biology in reproduction
▪ Imaging
▪ Mesoderm specification, and differentiation
▪ Neural stem cells
▪ Niche biology, homing, and migration
▪ Pluripotency
▪ Stem cell differentiation
▪ Stem cell homeostasis and function
▪ Stem cell renewal
▪ Stem cell immunology
▪ Tissue-specific stem cells
▪ Therapeutic prospects and clinical trials
▪ Tissue engineering, biomaterials, and manufacturing
▪ Research policies and ethical considerations.
Cancer stem cells
Cell maturation and aging
Cellular and nuclear reprogramming
Computational biology and data science
Disease modeling and drug discovery
Ectoderm specification and differentiation
Endoderm specification and differentiation
Genetics and epigenetics
Genomics, proteomics and omics
Germ cell and somatic stem cell biology in reproduction
Imaging
Mesoderm specification, and differentiation
Neural stem cells
Niche biology, homing, and migration
Pluripotency
Stem cell differentiation
Stem cell homeostasis and function
Stem cell renewal
Stem cell immunology
Tissue-specific stem cells
Therapeutic prospects and clinical trials
Tissue engineering, biomaterials, and manufacturing
Research policies and ethical considerations.

If you have a specific questions, please get in touch by mail: stemjournal@iospress.com.

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Submit Your Stem Cell Research Here!

StemJournal publishes original, peer-reviewed content covering a wide range of topics related to stem cell research. More details here.

Why submit to our open access stem cell journal?

The many benefits for contributing authors include:
• First class Editorial Board (see here)
• Hassle free submission process via Editorial Manager (see here)
• Rigorous peer review and speedy manuscript processing
• Rapid online publication (pre-press)
• Significantly reduced article processing charge for papers accepted in 2021.

As an additional benefit, authors of accepted papers are invited to join the StemJournal Editorial Advisory Board. Read more here.

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