Dear Colleague, We are delighted to announce the publication of Volume 7, Issue 3 of the Journal of Huntington’s Disease (JHD). This issue contains two open acess articles: a review article describing the current evidence linking wild-type and mutant huntingtin to cancer; and the latest installment of the Huntington's Disease (HD) Clinical Trials Corner. The full contents of this issue can be accessed from the list below. Kind regards, Editors-in-Chief Blair R. Leavitt, MD, CM The University of British Columbia Vancouver, BC, Canada b.leavitt@iospress.com Leslie M. Thompson, PhD University of California, Irvine Irvine, CA, USA l.thompson@iospress.com | Click on links below to view more: Review Article Cancer: From Wild-Type to Mutant Huntingtin – Open Access Thion, Morgane Sonia | Humbert, Sandrine Research Articles Reduced Cancer Incidence in Huntington’s Disease: Analysis in the Registry Study McNulty, Paul | Pilcher, Richard | Ramesh, Raviram | Necuiniate, Renata | Hughes, Alis | REGISTRY Investigators of the European Huntington's Disease Network (EHDN) | Farewell, Daniel | Holmans, Peter | Jones, Lesley Computational Analysis of Transcriptional Regulation Sites at the HTT Gene Locus De Souza, Rebecca A.G. | Kosior, Natalia | Thomson, Sarah B. | Mathelier, Anthony | Zhang, Allen W. | Bečanović, Kristina | Wasserman, Wyeth W. | Leavitt, Blair R. Suicidal Ideation Assessment in Individuals with Premanifest and Manifest Huntington Disease Wesson, Melissa | Boileau, Nicholas R. | Perlmutter, Joel S. | Paulsen, Jane S. | Barton, Stacey K. | McCormack, Michael K. | Carlozzi, Noelle E. Marriage as Protector for Nursing Home Admission in Huntington’s Disease Winder, Jessica Y. | Achterberg, Wilco P. | Roos, Raymund A.C. Anorectal Dysfunction in Presymptomatic Mutation Carriers and Patients with Huntington’s Disease Kobal, Jan | Matej, Kolenc | Koželj, Matic | Podnar, Simon Vocalisation as a Viable Assessment for Phenotyping Minipigs Transgenic for the Huntington Gene? Rieke, Lorena | Schubert, Robin | Matheis, Tamara | Muratori, Lisa M. | Motlik, Jan | Schramke, Sarah | Fels, Michaela | Kemper, Nicole | Schuldenzucker, Verena | Reilmann, Ralf Other Content Huntington’s Disease Clinical Trials Corner: August 2018 – Open Access Rodrigues, Filipe B. | Wild, Edward J. Upcoming Meetings Related to Huntington’s Disease – Openly Available | Most Read JHD Articles in June & July 2018 Striatal Mutant Huntingtin Protein Levels Decline with Age in Homozygous Huntington’s Disease Knock-In Mouse Models – Open Access (Research Article in Vol.7, Iss.2, 2018) Franich, Nicholas R. | Basso, Manuela | André, Emily A. | Ochaba, Joseph | Kumar, Amit | Thein, Soe | Fote, Gianna | Kachemov, Marketta | Lau, Alice L. | Yeung, Sylvia Y. | Osmand, Alexander | Zeitlin, Scott O. | Ratan, Rajiv R. | Thompson, Leslie M. | Steffan, Joan S. A Fresh Look at Huntingtin mRNA Processing in Huntington’s Diseas – Open Access (Review Article in Vol.7, Iss.2, 2018) Romo, Lindsay | Mohn, Emily S. | Aronin, Neil Aquatherapy for Neurodegenerative Disorders – Open Access (Review Article in Vol.3, Iss.1, 2014) Plecash, Alyson R. | Leavitt, Blair R. Physical Therapy and Exercise Interventions in Huntington’s Disease: A Mixed Methods Systematic Review – Open Access (Research Article in Vol.6, Iss.3, 2017) Fritz, Nora E. | Rao, Ashwini K. | Kegelmeyer, Deb | Kloos, Anne | Busse, Monica | Hartel, Lynda | Carrier, Judith | Quinn, Lori Huntington’s Disease Outpatient Clinic for Functional Diagnosis and Treatment: Coming to Consensus: How Long Term Care Facility Procedures Complement Specialist Diagnosis and Treatment – Open Access (Commentary in Vol.7, Iss.2, 2018) Veenhuizen, Ruth | Nijsten, Hanneke | van Roosmalen, Paul | Lammertsen, Karen | Stor, Tom | de Jager, Lia | de Man, Jesseke | van der Doelen, Rina | Landa, Karin | Grond, Vera | Heffels, Joyce | Groenewoud, Rinske | Rovers, Luce | Bakker, Christian | Leiwakabessy, Saskia | van der Wedden, Dirk | van Blitterswijk, Jacqueline | van den Bosch, Dieuwke | EHDN Plenary Meeting 2018 September 14–16, 2018 | Vienna, Austria The European Huntington’s Disease Network (EHDN) aims to facilitate research in order to advance knowledge and develop effective therapies for HD. An example is seen in the new issue of JHD, where a research study investigating cancer incidence in JHD utilized data from the EHDN's REGISTRY. The EHDN Plenary Meeting in Vienna in September will include a series of plenary sessions of interest to clinicians, scientists, and the wider HD community. Topics presented will feature reports on recent advances in HD research (in both basic and clinical sciences). If you plan to attend, further details are available on the EHDN event website (registration is now closed). JHD information will be available to delegates at EHDN 2018 in Vienna: we encourage delegates to consider submitting research to the journal. | HSG Annual Meeting 2018 November 8–10, 2018 | Houston, TX, USA The Huntington Study Group (HSG) hosts an annual, internationally recognized forum for training and education of HD researchers, and for presentation of new research findings and treatments to the worldwide community, plus much more. This year's HSG Annual Meeting will take place in Houston, TX, USA in November and registration is now open. For more information, view the HSG website here. | Sign Ups & Social Media Help Spread the News of JHD! | If you know of any colleagues or fellow researchers who are not yet signed up to receive the newsletter, we invite you to share this mailing with them. Click on the sign-up link at the bottom of this email or access here. JHD has had a successful socia media presence for a number of years, and recently there have been some developments. Joan Steffan has stepped down as social media editor and we would like to thank Joan for her sterling job running the JHD Facebook account. The new social media editor, Lauren Byrne, joined the JHD team last month: welcome Lauren! If you are not yet interacting with JHD on social media, why not take the time today to follow us on Twitter (NEW) and find us on Facebook? Be part of the discussion! | |