Volume 76, Issue 2 / 2020 Online

ARTICLE COMMENTARY (View more COVID-19 content here)
Dementia Care in the Time of COVID-19 Pandemic – Openly Available
Tousi, Babak

REVIEW ARTICLES
Ethical Issues Raised by the Introduction of Artificial Companions to Older Adults with Cognitive Impairment: A Call for Interdisciplinary Collaborations
Portacolone, Elena | Halpern, Jodi | Luxenberg, Jay | Harrison, Krista L. | Covinsky, Kenneth E.

Realizing the Potential of Robotics for Aged Care Through Co-Creation
Robillard, Julie M. | Kabacińska, Katarzyna

RESEARCH ARTICLES
Addressing the Ethics of Telepresence Applications Through End-User Engagement
Robillard, Julie M. | Goldman, Ian P. | Prescott, Tony J. | Michaud, François

Becoming or Remaining Agitated: The Course of Agitation in People with Dementia Living in Care Homes. The English Longitudinal Managing Agitation and Raising Quality of Life (MARQUE) Study
Marston, Louise | Livingston, Gill | Laybourne, Anne | Cooper, Claudia

A Twin Study of Sex Differences in Genetic Risk for All Dementia, Alzheimer’s Disease (AD), and Non-AD Dementia
Beam, Christopher R. | Kaneshiro, Cody | Jang, Jung Yun | Reynolds, Chandra A. | Pedersen, Nancy L. | Gatz, Margaret

Endostatin as a Mediator Between Endothelial Function and Cognitive Performance in Those at Risk for Vascular Cognitive Impairment – Open Access
Isaacs-Trepanier, Cameron | Saleem, Mahwesh | Herrmann, Nathan | Swardfager, Walter | Oh, Paul I. | Goldstein, Benjamin I. | Mitchell, Jane | Sugamori, Kim S. | Lanctôt, Krista L.

Selective Peripheral Taste Dysfunction in APP/PS1 Mutant Transgenic Mice
Wood, Ryan M. | Garcia, Zacnite | Daniels, Nathan | Landon, Shannon M. | Humayun, Saima | Lee, Hyoung-gon | Macpherson, Lindsey J.

Design and Rationale of the PACt-MD Randomized Clinical Trial: Prevention of Alzheimer’s dementia with Cognitive remediation plus transcranial direct current stimulation in Mild cognitive impairment and Depression
Rajji, Tarek K. | Bowie, Christopher R. | Herrmann, Nathan | Pollock, Bruce G. | Bikson, Marom | Blumberger, Daniel M. | Butters, Meryl A. | Daskalakis, Zafiris J. | Fischer, Corinne E. | et al.

The Efficacy of Sertraline, Escitalopram, and Nicergoline in the Treatment of Depression and Apathy in Alzheimer’s Disease: The Okayama Depression and Apathy Project
Takemoto, Mami | Ohta, Yasuyuki | Hishikawa, Nozomi | Yamashita, Toru | Nomura, Emi | Tsunoda, Keiichiro | Sasaki, Ryo | Tadokoro, Koh | Matsumoto, Namiko | Omote, Yoshio | Abe, Koji

Volume 76, Issue 1 / 2020 Online

EDITORIALS (View more COVID-19 content here)
Alzheimer’s Disease Patients in the Crosshairs of COVID-19 – Openly Available
Perry, George

Hypothesis: Does the Apparent Protective Action of Green Valley’s Drug GV971 Against Cognitive Decline Result from Antiviral Action Against Herpes Simplex Virus Type 1 in Brain?
Itzhaki, Ruth F.

REVIEW ARTICLES
Neurobiology of COVID-19 – Openly Available
Fotuhi, Majid | Mian, Ali | Meysami, Somayeh | Raji, Cyrus A.

The Role of Synaptic Dysfunction in Alzheimer’s Disease
Pei, Yixuan (Amy) | Davies, Julie | Zhang, Melanie | Zhang, Han-Ting

Hemodynamic Instability in Heart Failure Intensifies Age-Dependent Cognitive Decline
de la Torre, Jack C.

RESEARCH ARTICLES
APOE4 Status is Related to Differences in Memory-Related Brain Function in Asymptomatic Older Adults with Family History of Alzheimer’s Disease: Baseline Analysis of the PREVENT-AD Task Functional MRI Dataset – Open Access
Rabipour, Sheida | Rajagopal, Sricharana | Yu, Elsa | Pasvanis, Stamatoula | Lafaille-Magnan, Marie-Elyse | Breitner, John | PREVENT-AD Research Group | Rajah, M. Natasha

Mid- and Late-Life Leisure-Time Physical Activity and Global Brain Amyloid Burden: The Atherosclerosis Risk in Communities (ARIC)-PET Study
Palta, Priya | Heiss, Gerardo | Sharrett, A. Richey | Gabriel, Kelley Pettee | Walker, Keenan | Evenson, Kelly R. | Knopman, David | Mosley, Thomas H. | Wong, Dean F. | Gottesman, Rebecca F.

Brain Structure in Bilingual Compared to Monolingual Individuals with Alzheimer’s Disease: Proof of Concept
Raji, Cyrus A. | Meysami, Somayeh | Merrill, David A. | Porter, Verna R. | Mendez, Mario F.

Serum Hepcidin Levels in Cognitively Normal Older Adults with High Neocortical Amyloid-β Load – Open Access
Chatterjee, Pratishtha | Mohammadi, Maryam | Goozee, Kathryn | Shah, Tejal M. | Sohrabi, Hamid R. | Dias, Cintia B. | Shen, Kaikai | Asih, Prita R. | Dave, Preeti | Pedrini, Steve | et al.

Relationships Between Plasma Lipids Species, Gender, Risk Factors, and Alzheimer’s Disease – Open Access
Lim, Wei Ling Florence | Huynh, Kevin | Chatterjee, Pratishtha | Martins, Ian | Jayawardana, Kaushala S. | Giles, Corey | Mellett, Natalie A. | Laws, Simon M. | Bush, Ashley I. | et al..

Cerebrospinal Fluid (CSF) Exchange Therapy with Artificial CSF Enriched with Mesenchymal Stem Cell Secretions Ameliorates Cognitive Deficits and Brain Pathology in Alzheimer’s Disease Mice
Benhamron, Sandrine | Nitzan, Keren | Valitsky, Michael | Lax, Neta | Karussis, Dimitrios | Kassis, Ibrahim | Rosenmann, Hanna

Supplementation with Matured Hop Bitter Acids Improves Cognitive Performance and Mood State in Healthy Older Adults with Subjective Cognitive Decline – Open Access
Fukuda, Takafumi | Ohnuma, Tohru | Obara, Kuniaki | Kondo, Sumio | Arai, Heii | Ano, Yasuhisa

JAD now has an Impact Factor of 3.909 and a 5 Year Impact Factor of 4.023, according to the recently released 2019 Journal Citation Reports.*

The number of citations to papers published in JAD continues to increase. and, in fact, JAD is the most-cited Alzheimer's journal in the Neurosciences category in Web of Science.*

*Journal Citation Reports (Source: Clarivate, 2020)

We thank our authors, reviewers and readers for the continuing success of JAD.

2020 Alzheimer Award Winners

JAD is proud to announce that Christin Nance, BA, and Sarah Banks, PhD, are the joint recipients of the 2020 Alzheimer Award. Each year, JAD’s Associate Editors select the article published during the previous year that has had the most significant impact on Alzheimer’s disease (AD) research. The winning article addresses one of the primary challenges in managing AD: the variable rate of cognitive decline among patients. Individuals diagnosed with AD who experience rapid cognitive decline are associated with worse functional outcomes and a higher mortality rate than those with normal rates of cognitive decline.

View the full press release here

Open Access Winning Paper:
The Pathology of Rapid Cognitive Decline in Clinically Diagnosed Alzheimer’s Disease

The Journal of Alzheimer's Disease Reports – JAD's sister journal – is our online-only, fully open access journal for AD papers that gives equal weight to original research in basic science, translational research and clinical studies. We encourage direct submissions to Journal of Alzheimer's Disease Reports, taking advantage of the open access option and accelerated publication timeline (see instructions here).

Recent COVID-19 content published in the journal:

Neurologic and Immunologic Complications of COVID-19: Potential Long-Term Risk Factors for Alzheimer’s Disease
Lennon, Jack C.

Dementia and COVID-19 Lockdown: More Than a Double Blow for Patients and Caregivers
Migliaccio, Raffaella | Bouzigues, Arabella

View content highlights published in Q2, 2020 in Vol.4 here